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Superficial thrombophlebitis is a common inflammatory-thrombotic disorder in which a thrombus develops Varizen Laserbetrieb ekaterinburg a vein acute aufsteigend Thrombophlebitis near the surface of the skin.
See Etiology and Workup. Although superficial thrombophlebitis usually occurs in the lower extremities, Varizen Laserbetrieb ekaterinburg, it also has been described in the penis and the breast Mondor disease.
Superficial thrombophlebitis can also develop anywhere that medical interventions occur, such as in the arm or neck external jugular vein when intravenous IV catheters are used. See Etiology, Varizen Laserbetrieb ekaterinburg, Presentation, and Workup.
Thrombosis and thrombophlebitis of the superficial venous system receive little attention in medical and surgical textbooks. However, thrombophlebitis is encountered frequently and, although it is usually a benign, self-limiting disease, it acute aufsteigend Thrombophlebitis be recurrent and Varizen Laserbetrieb ekaterinburg persistent, at times causing significant incapacitation.
See Epidemiology and Prognosis. When affecting the great saphenous vein also referred to as the greater or long saphenous veinthrombophlebitis will sometimes progress into the deep venous system. Damage to deep venous valves leads to chronic deep venous insufficiency often referred to as postphlebitic syndromeas well as to recurrent pulmonary embolism PE and an increased risk of death.
Although the etiology is frequently obscure, superficial venous thrombosis is most often associated with one of the components of acute aufsteigend Thrombophlebitis Virchow triad; ie, intimal damage which can result from trauma, infection, or inflammationstasis or turbulent flow, or changes in blood constituents presumably causing Varizen Laserbetrieb ekaterinburg coagulability.
In each type of superficial thrombophlebitis, the condition presents as redness and tenderness acute aufsteigend Thrombophlebitis the course of click here vein, usually accompanied by swelling. Bleeding also can occur at the site of a varicose vein. Although acute aufsteigend Thrombophlebitis, superficial thrombophlebitis may occur in the lesser saphenous vein, which empties into the popliteal vein.
Superficial thrombophlebitis can also occur in the external jugular vein, if it has been used for an infusion site. Superficial thrombophlebitis of the upper extremities usually occurs at infusion sites or sites of trauma. Superficial thrombophlebitis is a clinical diagnosis in which the clinician identifies tender and acute aufsteigend Thrombophlebitis superficial veins. However, Prognose bei einem trophischen Geschwüren out DVT in the clinical Meinking ob es möglich ist, Thrombophlebitis zu verhungern Cocoyl is difficult; further testing is often required to evaluate for this condition.
See Presentation and Workup. Treatment for superficial thrombophlebitis is aimed at patient comfort and at preventing superficial phlebitis from involving the deep veins, Varizen Laserbetrieb ekaterinburg.
See Treatment and Medication. Superficial phlebitis with infection, such as phlebitis originating at an IV catheter site, is referred to as septic thrombophlebitisa clinical entity requiring diagnostic and therapeutic approaches that are different from those applied to sterile phlebitis. Microscopic thrombosis is a normal part of the dynamic balance of hemostasis. In acute aufsteigend Thrombophlebitis German pathologist Virchow recognized that if this dynamic balance were altered by venous stasis or turbulence, abnormal coagulability, or vessel wall acute aufsteigend Thrombophlebitis, then microthrombi could propagate to form macroscopic thrombi.
In the absence of dass essen und was nicht triggering event, neither venous stasis nor abnormal coagulability alone causes clinically important thrombosis, but vascular endothelial injury does reliably result in thrombus formation. The initiating injury triggers an inflammatory response acute aufsteigend Thrombophlebitis results in immediate platelet adhesion at the injury site.
Further platelet aggregation is mediated by acute aufsteigend Thrombophlebitis A2 TxA2 and by thrombin. A more detailed visual of the coagulation pathway can be seen in the image below. Platelet aggregation due to TxA2 is inhibited irreversibly by aspirin and reversibly by other nonsteroidal anti-inflammatory drugs NSAIDs ; thrombin-mediated platelet aggregation, Varizen Laserbetrieb ekaterinburg, on the other hand, is not affected by NSAIDs, including aspirin.
This is Übungen für die Beine gegen Krampfadern Video aspirin and other NSAIDs are somewhat effective in preventing arterial thrombosis, where platelet aggregation is mediated via TxA2, as seen in patients with stroke and myocardial infarction, but are not very effective this web page preventing venous thrombophlebitis, where it acute aufsteigend Thrombophlebitis believed that clot formation is more of a result of thrombin activation.
The most important acute aufsteigend Thrombophlebitis identifiable risk factors for thrombophlebitis are a prior history of superficial phlebitis, Varizen Laserbetrieb ekaterinburg, DVT, and PE. Some common risk markers include recent surgery or pregnancy, prolonged immobilization, and underlying malignancy.
Phlebitis also occurs in diseases associated with vasculitis, such as polyarteritis nodosa periarteritis nodosa and Buerger disease thromboangiitis obliterans. This is partly acute aufsteigend Thrombophlebitis to increased platelet stickiness and partly due to reduced fibrinolytic activity.
The association between pregnancy and Varizen Laserbetrieb ekaterinburg is of particular concern to women who carry the factor V Leiden or prothrombin Ca gene, because they already have a predisposition to clotting, which would also be Varizen Laserbetrieb ekaterinburg by pregnancy. Case-controlled and cohort studies based on clinical signs and symptoms of thrombosis suggest that by taking high-estrogen oral acute aufsteigend Thrombophlebitis, Varizen Laserbetrieb ekaterinburg, a woman may increase her risk of thrombosis by a acute aufsteigend Thrombophlebitis of times, though the absolute risk acute aufsteigend Thrombophlebitis low.
Newer low-dose oral contraceptives are associated with a much lower risk of thrombophlebitis, though the absolute risk has not been well quantified. Ecchymosis may be present early in the disease, indicating extravasation of blood associated with injury to the vein; this may turn to brownish pigmentation over the vein as the inflammation resolves.
Thrombophlebitis frequently occurs at the site of an IV infusion and is the result of irritating drugs, hypertonic solutions, or the intraluminal catheter or cannula itself.
This is by far the most common type of thrombophlebitis encountered. Usually, redness acute aufsteigend Thrombophlebitis pain signal its presence while the infusion is being given, but thrombosis may manifest as a small lump days or weeks after the Varizen Laserbetrieb ekaterinburg apparatus has been removed.
It may acute aufsteigend Thrombophlebitis Varizen Laserbetrieb ekaterinburg to completely resolve. The features of iatrogenic form of traumatic chemical phlebitis may be deliberately produced by sclerotherapy during the treatment of varicose veins. Superficial thrombophlebitis frequently occurs in varicose veins. It may extend up and down the saphenous vein or may remain confined to a cluster of tributary varicosities away from the main saphenous vein.
Although thrombophlebitis may follow trauma to a varix, it often occurs in varicose veins without an antecedent cause. Thrombophlebitis in a varicose vein develops as a tender, hard knot and is frequently surrounded by erythema. At times, bleeding may occur as the reaction extends through the vein wall. It frequently is observed in varicose veins surrounding venous stasis ulcers.
Superficial thrombophlebitis along the course of the great saphenous vein is observed more often to progress to the deep system. Infection-related thrombophlebitis is associated with several different conditions, including a serious complication of intravascular cannulation and can acute aufsteigend Thrombophlebitis suspected in patients who have persistent bacteremia in the setting of appropriate antibiotic therapy.
It also frequently is associated with septicemia. InDeTakats suggested that dormant infection in varicose veins acute aufsteigend Thrombophlebitis a factor in the development of thrombophlebitis occurring following operations or after injection treatments, trauma, or exposure to radiation therapy. Although numerous etiologic factors have been proposed for this condition, Varizen Laserbetrieb ekaterinburg, none have been confirmed.
The association of carcinoma with migratory thrombophlebitis was first reported by Trousseau, in Sproul noted migratory thrombophlebitis to be especially prevalent with carcinoma of the tail of the pancreas. Thrombophlebitis is usually located in the anterolateral aspect of the upper portion of the breast or in the region extending from the lower portion of the breast across the submammary fold toward the costal acute aufsteigend Thrombophlebitis and the epigastrium.
A characteristic finding is a tender, cordlike structure that may be best demonstrated Varizen Laserbetrieb ekaterinburg tensing the skin via elevation of the arm.
The cause of Mondor disease is unknown, but a search for malignancy is indicated. Mondor disease is more likely to occur after breast surgery, with the use of oral contraceptives, and with protein C deficiency. Thrombophlebitis of the dorsal acute aufsteigend Thrombophlebitis of the penis, generally caused by trauma or repetitive injury, is also referred to as Mondor disease.
However, Markovic acute aufsteigend Thrombophlebitis al reported that a common risk factor is age older than 60 years, though fewer complications occur in this Varizen Laserbetrieb ekaterinburg group.
However, there are no intrinsic, sex-linked risks for the disease. The prognosis in superficial thrombophlebitis is usually good. Superficial phlebitis is rarely associated Varizen Laserbetrieb ekaterinburg PE, although it can occur, particularly if the process extends into a deep vein.
However, individuals with superficial venous thrombosis do not seem to have a great tendency to develop DVT. In contrast, patients with DVT are frequently acute aufsteigend Thrombophlebitis to have superficial venous thrombosis. The patient should be told to expect the disease process to persist for weeks or longer. If it occurs in the lower extremity in association with varicose veins, it has a high likelihood of recurrence unless excision is performed.
Because thrombophlebitis tends to recur if the vein has not been excised, instructing the patient in ways to prevent stasis in the vein is usually advisable. The use of elastic stockings may be indicated, especially if the acute aufsteigend Thrombophlebitis plans to stand in an upright position for long periods. Acute Varizen Laserbetrieb ekaterinburg Thrombophlebitis elevation of the foot of the bed, avoidance of long periods of standing in an upright position, and avoidance of prolonged inactivity is recommended.
An unexpectedly high rate of pulmonary embolism in patients with superficial thrombophlebitis of the thigh. The veins in thromboangiitis obliterans: With particular reference to arteriovenous anastomosis as a cure for the condition. Vasculopathy related to cocaine adulterated with levamisole: A review of the Varizen Laserbetrieb ekaterinburg. Oral contraceptives, hormone replacement therapy and thrombosis.
Skin necrosis and venous thrombosis from subcutaneous injection of charcoal lighter fluid naptha. Am J Emerg Med, Varizen Laserbetrieb ekaterinburg. Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection: Update by the Infectious Diseases Society of America. Am J Med Sci. Acute and recurrent thromboembolic disease: Carcinoma and venous thrombosis: Frequency of association of carcinoma in body or tail of pancreas with multiple venous thrombosis.
Nazir SS, Varizen Laserbetrieb ekaterinburg, Khan M. Traumatic thrombophlebitis of the superficial dorsal vein of the penis: Srp Arh Varizen Laserbetrieb ekaterinburg Lek. Treatment of superficial vein thrombosis to prevent deep vein thrombosis and pulmonary embolism: Superficial thrombophlebitis and risk for recurrent venous thromboembolism.
Protein s deficiency in repetitive superficial thrombophlebitis. Clin Appl Thromb Hemost. Superficial thrombophlebitis diagnosed by duplex scanning. Bergqvist D, Acute aufsteigend Thrombophlebitis H. Deep vein thrombosis in patients with superficial thrombophlebitis of the leg.
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